The incidence of HBeAg in HBsAg positive hemodialysis patients in reported. 21.2% of hemodialysis patients have been resulted positive for serum HBsAg. 63.6% of HBsAg positive patients resulted to have HBeAg in their serum. Anti-HBe antibody was never found. The Authors emphasize the importance of HBeAg in hemodialysis patients to evaluate their infectivity.