The authors present the results of a study carried on 25 cases (Hodgkin patients) performing before and after standardized radiotherapy on retroperitoneal lymph nodes (45 Gy): - radionephrography and determination of renal plasmatic flux and glomerular filtration; - liver scintigraphy by colloids and 99Tcm-HIDA and liver functional tests by 131I-Bengal rose; - pancreas scintigraphy. Focal damage of the hepatic left lobe in younger patients and transitory impairment of some renal functional tests have been observed.