Effect of the alpha-agonist noradrenaline on total and 45Ca2+ movements in mitochondria of rat liver cells

Biochem J. 1981 Oct 15;200(1):177-80. doi: 10.1042/bj2000177.

Abstract

Ca(2+) movements triggered by noradrenaline were determined in isolated cells and mitochondria from rat livers. It has been shown that these depend on experimental conditions. In cells incubated in 1.8mm-Ca(2+), results suggest that noradrenaline mobilizes Ca(2+) from reticulum before releasing Ca(2+) from mitochondria.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Caffeine / pharmacology
  • Calcium / metabolism*
  • Female
  • In Vitro Techniques
  • Liver / cytology
  • Liver / drug effects
  • Mitochondria, Liver / drug effects
  • Mitochondria, Liver / metabolism*
  • Norepinephrine / pharmacology*
  • Rats
  • Rats, Inbred Strains
  • Time Factors

Substances

  • Caffeine
  • Calcium
  • Norepinephrine