Effect of lipid soluble antioxidants on cytotoxicity induced by photochemical products of cholesterol

Experientia. 1980 Apr 15;36(4):439-40. doi: 10.1007/BF01975135.

Abstract

Lipid soluble antioxidants, butylated hydroxytoluene and vitamin E, were shown to suppress cytotoxicity induced by cholesterol-derived photoproducts in Chinese hamster embryo cells. These cholesterol-derived photoproducts were rather toxic.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Antioxidants*
  • Butylated Hydroxytoluene / pharmacology*
  • Cell Survival / drug effects
  • Cells, Cultured
  • Cholesterol / analogs & derivatives*
  • Cholesterol / pharmacology
  • Cricetinae
  • Cricetulus
  • Embryo, Mammalian
  • Photochemistry
  • Vitamin E / pharmacology*

Substances

  • Antioxidants
  • Vitamin E
  • Butylated Hydroxytoluene
  • Cholesterol