A test of the hypothesis that time to tumor in humans fits the "one-hit" model

J Environ Pathol Toxicol. 1980 Aug;4(1):139-43.

Abstract

Data from the Connecticut Tumor Registry for 1935-1968 for 14 tumor sites were subjected to formal statistical tests of the hypothesis that the time to tumor has an exponential distribution (and hence is a result of one random "hit"). All of the resulting 270 test statistics rejected the hypothesis.

MeSH terms

  • Age Factors
  • Connecticut
  • Humans
  • Models, Biological
  • Neoplasms / epidemiology*
  • Registries
  • Time Factors