Characterization of a new antibiotic of iturin group: bacillomycin D

J Antibiot (Tokyo). 1980 Oct;33(10):1146-9. doi: 10.7164/antibiotics.33.1146.

Abstract

The characterization of an antibiotic isolated from a strain of Bacillus subtilis revealed that this compound is a new antifungal antibiotic of the iturin group. It contains a lipid moiety which is a mixture of 3-amino 12-methyl tridecanoic acid (40%) and 3-amino 12-methyl tetradecanoic acid (60%) and a peptide moiety: L-Asp1, D-Asp1, L-Glu1, L-Pro1, D-Ser1, L-Thr1 and D-Tyr1. These two moieties are joined by a threonyl-beta-aminoacid linkage.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents* / analysis*
  • Anti-Bacterial Agents* / isolation & purification
  • Antimicrobial Cationic Peptides
  • Chemical Phenomena
  • Chemistry, Physical
  • Hydrolysis
  • Peptides*
  • Peptides, Cyclic / analysis
  • Peptides, Cyclic / isolation & purification

Substances

  • Anti-Bacterial Agents
  • Antimicrobial Cationic Peptides
  • Peptides
  • Peptides, Cyclic
  • bacillomycin D