Specific detection of Campylobacter concisus by PCR amplification of 23S rDNA areas

Mol Cell Probes. 1995 Aug;9(4):247-50. doi: 10.1016/s0890-8508(95)90114-0.

Abstract

The phenotypic detection of Campylobacter concisus, a species of considerable genomic and phenotypic heterogeneity, has proven to be rather tedious in the past. Although alternative methods like DNA:DNA hybridization, immunotyping or whole-cell protein electrophoresis are valuable for the specific detection of C. concisus, they are too laborious to be performed in routine settings. Hence a simple Campylobacter concisus-specific PCR assay was developed, based on a target sequence which comprises the most variable areas of 23S rDNA. The PCR assay was successfully evaluated on a broad selection of C. concisus strains and phylogenetically related bacteria.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacterial Typing Techniques
  • Base Sequence
  • Campylobacter / classification
  • Campylobacter / genetics
  • Campylobacter / isolation & purification*
  • DNA, Bacterial / genetics*
  • DNA, Ribosomal / genetics*
  • Molecular Sequence Data
  • Phylogeny
  • Polymerase Chain Reaction
  • RNA, Ribosomal, 23S / genetics

Substances

  • DNA, Bacterial
  • DNA, Ribosomal
  • RNA, Ribosomal, 23S