Abstract
We investigated the effects of 10 mg aerosolized furosemide on clinical score in 28 acutely wheezing infants (Part A) and in a second group of 20 intermittently wheezing babies on airway resistance and functional residual capacity during a symptomfree period (Part B), using a double-blind, placebo-controlled design. In both parts of the study no therapeutic effects were observed during and following aerosol inhalation of 10 mg furosemide.
Publication types
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Clinical Trial
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Randomized Controlled Trial
MeSH terms
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Administration, Inhalation
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Aerosols
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Airway Resistance / drug effects
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Airway Resistance / physiology
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Anti-Asthmatic Agents / administration & dosage*
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Bronchiolitis / drug therapy*
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Bronchiolitis / physiopathology
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Double-Blind Method
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Female
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Functional Residual Capacity / drug effects
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Functional Residual Capacity / physiology
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Furosemide / administration & dosage*
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Humans
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Infant
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Male
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Respiratory Sounds / drug effects*
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Respiratory Sounds / physiopathology
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Treatment Failure
Substances
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Aerosols
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Anti-Asthmatic Agents
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Furosemide