HIV-enteropathy and bile acid malabsorption: response to cholestyramine

M Steuerwald; H C Bucher; J Müller-Brand; M Götze; H W Roser; K Gyr

HIV-enteropathy and bile acid malabsorption: response to cholestyramine

Am J Gastroenterol. 1995 Nov;90(11):2051-3.

Authors

M Steuerwald¹, H C Bucher, J Müller-Brand, M Götze, H W Roser, K Gyr

Affiliation

¹ Department of Internal Medicine, University Hospital, Kantonsspital Basel, Switzerland.

PMID: 7485023

Abstract

Chronic diarrhea and weight loss are common in patients with AIDS. We report on an AIDS patient with chronic diarrhea, steatorrhea, and marked weight loss. A 75SeHCAT test demonstrated that the diarrhea was mainly due to bile acid malabsorption. Therapy with cholestyramine dramatically reduced bowel movements and led to significant reversal of weight loss.

Publication types

Case Reports

MeSH terms

AIDS-Related Opportunistic Infections / diagnosis
Adult
Bile Acids and Salts / metabolism*
Cholestyramine Resin / therapeutic use*
HIV Enteropathy / complications
HIV Enteropathy / drug therapy*
HIV Enteropathy / metabolism
Humans
Malabsorption Syndromes / complications
Malabsorption Syndromes / diagnosis
Malabsorption Syndromes / drug therapy*
Malabsorption Syndromes / metabolism
Male
Selenium Radioisotopes
Taurocholic Acid / analogs & derivatives

Substances

Bile Acids and Salts
Selenium Radioisotopes
Cholestyramine Resin
Taurocholic Acid
23-seleno-25-homotaurocholic acid