Nephron sparing surgery for renal cell carcinoma in von Hippel-Lindau disease

J Urol. 1995 Dec;154(6):2016-9.

Abstract

Purpose: We evaluated the technical feasibility and followup outcomes of a nephron sparing operation for localized renal cell carcinoma and von Hippel-Lindau disease.

Materials and methods: Our 5 patients underwent initial nephron sparing surgery followed by serial computerized tomography.

Results: All but 1 renal lesion was resected in 9 initial nephron sparing operations. Postoperative computerized tomography revealed 35 lesions of which 8 had enlarged. Four patients underwent secondary renal surgery and adequate renal function was preserved.

Conclusions: Even with the high risk of local recurrence nephron sparing surgery is an appropriate approach for these patients.

Publication types

  • Clinical Trial

MeSH terms

  • Adult
  • Carcinoma, Renal Cell / diagnostic imaging
  • Carcinoma, Renal Cell / etiology
  • Carcinoma, Renal Cell / surgery*
  • Female
  • Follow-Up Studies
  • Humans
  • Kidney Neoplasms / diagnostic imaging
  • Kidney Neoplasms / etiology
  • Kidney Neoplasms / surgery*
  • Male
  • Middle Aged
  • Nephrons
  • Surgical Procedures, Operative / methods
  • Tomography, X-Ray Computed
  • von Hippel-Lindau Disease / complications*
  • von Hippel-Lindau Disease / diagnostic imaging