Abstract
Vochysia divergens Pohl (Vochysiaceae) is a tree commonly found in wet soils of 'Pantanal' of Mato Grosso, Brazil, and used in folk medicine against infections and asthma. We have studied different extracts and some isolated compounds from this plant for antibacterial activity. From the extracts of the stem bark beta-sitosterol, betulinic acid and sericic acid were isolated. The minimal inhibitory concentration (MIC) for Staphylococcus aureus were: ethanolic extract (MIC = 1.5 mg/ml); ethyl acetate extract (MIC = 2.0 mg/ml); and sericic acid (MIC = 1.0 mg/ml). Escherichia coli was resistant until 5 mg/ml.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Bacterial Agents / pharmacology*
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Antineoplastic Agents, Phytogenic / isolation & purification
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Antineoplastic Agents, Phytogenic / pharmacology
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Betulinic Acid
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Brazil
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Escherichia coli / drug effects*
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Magnetic Resonance Spectroscopy
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Medicine, Traditional
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Microbial Sensitivity Tests
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Oleanolic Acid / analogs & derivatives
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Oleanolic Acid / isolation & purification
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Oleanolic Acid / pharmacology
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Pentacyclic Triterpenes
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Plant Extracts / pharmacology*
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Plant Stems / metabolism
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Sitosterols / isolation & purification
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Sitosterols / pharmacology
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Spectrophotometry, Infrared
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Staphylococcus aureus / drug effects*
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Triterpenes / isolation & purification
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Triterpenes / pharmacology
Substances
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Anti-Bacterial Agents
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Antineoplastic Agents, Phytogenic
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Pentacyclic Triterpenes
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Plant Extracts
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Sitosterols
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Triterpenes
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sericic acid
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gamma-sitosterol
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Oleanolic Acid
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Betulinic Acid