Abstract
Many striped dolphins (Stenella coeruleoalba) which died in the recent morbillivirus epizootic in the Mediterranean Sea had hyaline inclusions in hepatocytes. We investigated the histological, histochemical and ultrastructural features of these inclusions in two affected dolphins. Histochemical tests indicated that they contained glycoprotein but not lipid. Ultrastructurally, they consisted of granular, moderately electron-dense material, bounded by a membrane. A central or eccentric core of highly electron-dense material was usually apparent. The inclusions were probably of lysosomal origin.
MeSH terms
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Animal Diseases / epidemiology
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Animal Diseases / microbiology
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Animal Diseases / pathology
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Animals
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Antigens, Viral / analysis
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Bronchopneumonia / epidemiology
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Bronchopneumonia / microbiology
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Bronchopneumonia / pathology
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Bronchopneumonia / veterinary
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Disease Outbreaks / veterinary
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Dolphins / anatomy & histology*
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Glycoproteins / analysis
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Hepatitis, Viral, Animal / epidemiology
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Hepatitis, Viral, Animal / microbiology
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Hepatitis, Viral, Animal / pathology*
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Inclusion Bodies / chemistry
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Inclusion Bodies / ultrastructure*
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Italy / epidemiology
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Liver / pathology*
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Lung / pathology
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Lysosomes / ultrastructure
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Mediterranean Sea
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Morbillivirus / immunology
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Morbillivirus / isolation & purification
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Morbillivirus Infections / epidemiology
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Morbillivirus Infections / pathology
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Morbillivirus Infections / veterinary*
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Periodic Acid-Schiff Reaction
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Polychlorinated Biphenyls / adverse effects
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Staining and Labeling
Substances
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Antigens, Viral
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Glycoproteins
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Polychlorinated Biphenyls