Cystic fibrosis gene therapy using an adenovirus vector: in vivo safety and efficacy in nasal epithelium

MeSH terms

• Adenoviruses, Human* / physiology
• Administration, Intranasal
• Clinical Protocols
• Containment of Biohazards
• Cystic Fibrosis / genetics
• Cystic Fibrosis / therapy*
• Cystic Fibrosis Transmembrane Conductance Regulator
• Defective Viruses* / physiology
• Epithelium
• Evaluation Studies as Topic
• Genetic Therapy* / adverse effects
• Genetic Therapy* / methods
• Genetic Vectors*
• Humans
• Membrane Proteins / genetics
• Nasal Mucosa*
• Risk
• Safety
• Virus Replication