Abstract
In the chorionic plate and stem villi of the human placenta besides the fetal blood vessel system a second extravascular contractile system (EVCS) exists. The cells of this system contain contractile and intermediate filaments and are dipeptidyl peptidase-IV- and NO-synthase-type-I-(NOS)-immunoreactive. Therefore it can be assumed that these cells cleave the vasodilator Substance P (by DPP IV) and produce NO (by NOS) and may contribute to a modulation of the EVCS.
Publication types
-
English Abstract
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Amino Acid Oxidoreductases / physiology
-
Contractile Proteins / physiology*
-
Contractile Proteins / ultrastructure
-
Culture Techniques
-
Dipeptidyl Peptidase 4
-
Dipeptidyl-Peptidases and Tripeptidyl-Peptidases / physiology
-
Female
-
Humans
-
Immunohistochemistry
-
Intermediate Filaments / physiology
-
Intermediate Filaments / ultrastructure
-
Microscopy, Electron
-
Nitric Oxide Synthase
-
Placenta / anatomy & histology
-
Placenta / physiology*
-
Pregnancy
-
Substance P / metabolism
Substances
-
Contractile Proteins
-
Substance P
-
Nitric Oxide Synthase
-
Amino Acid Oxidoreductases
-
Dipeptidyl-Peptidases and Tripeptidyl-Peptidases
-
Dipeptidyl Peptidase 4