Abstract
A case of lung fibrosis is presented in a 44 year old male in whom interstitial pulmonary changes were observed in the course of bleomycin therapy of malignant granulomatosis. Following introduction of corticosteroids a radiological, clinical and functional improvement was observed. The functional changes were analyzed during the 7 month period of treatment. This case suggests that post bleomycin induced injury can be reversed with appropriate high doses of corticosteroids.
Publication types
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Case Reports
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English Abstract
MeSH terms
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Adult
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use
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Bleomycin / administration & dosage
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Bleomycin / adverse effects*
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Cisplatin / administration & dosage
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Hodgkin Disease / drug therapy
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Humans
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Lung Neoplasms / drug therapy
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Male
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Mechlorethamine / administration & dosage
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Prednisone / administration & dosage
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Procarbazine / administration & dosage
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Pulmonary Fibrosis / chemically induced*
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Vincristine / administration & dosage
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Vindesine / administration & dosage
Substances
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Bleomycin
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Procarbazine
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Mechlorethamine
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Vincristine
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Cisplatin
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Vindesine
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Prednisone
Supplementary concepts
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CVB protocol
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MOPP protocol