Tachykinin non-peptide antagonists: binding domain and molecular mode of action

Biochem Soc Trans. 1995 Feb;23(1):96-102. doi: 10.1042/bst0230096.
No abstract available

Publication types

  • Review

MeSH terms

  • Animals
  • Benzamides / metabolism
  • Benzamides / pharmacology
  • Binding Sites
  • Binding, Competitive
  • Biphenyl Compounds / metabolism
  • Biphenyl Compounds / pharmacology
  • GTP-Binding Proteins / metabolism*
  • Humans
  • Kinetics
  • Mutagenesis, Site-Directed
  • Neurokinin A / metabolism
  • Neurokinin A / pharmacology
  • Piperidines / metabolism
  • Piperidines / pharmacology
  • Point Mutation
  • Protein Structure, Secondary*
  • Receptors, Tachykinin / antagonists & inhibitors*
  • Receptors, Tachykinin / chemistry
  • Recombinant Fusion Proteins / antagonists & inhibitors
  • Recombinant Fusion Proteins / chemistry
  • Substance P / metabolism
  • Substance P / pharmacology
  • Tachykinins / antagonists & inhibitors*
  • Tachykinins / chemistry*
  • Tachykinins / metabolism

Substances

  • Benzamides
  • Biphenyl Compounds
  • Piperidines
  • Receptors, Tachykinin
  • Recombinant Fusion Proteins
  • Tachykinins
  • Substance P
  • SR 48968
  • Neurokinin A
  • GTP-Binding Proteins
  • CP 96345