Signal transduction through IL-6 receptor: involvement of multiple protein kinases, stat factors, and a novel H7-sensitive pathway

Ann N Y Acad Sci. 1995 Jul 21:762:55-70. doi: 10.1111/j.1749-6632.1995.tb32314.x.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine
  • Animals
  • Antigens, CD*
  • Base Sequence
  • Cloning, Molecular
  • Cytokine Receptor gp130
  • DNA-Binding Proteins / physiology
  • Genes, jun
  • Humans
  • Isoquinolines / pharmacology
  • Janus Kinase 1
  • Janus Kinase 2
  • Membrane Glycoproteins / physiology*
  • Mice
  • Molecular Sequence Data
  • Phosphotyrosine
  • Piperazines / pharmacology
  • Promoter Regions, Genetic
  • Protein Kinase Inhibitors
  • Protein Kinases / physiology*
  • Protein-Tyrosine Kinases / metabolism
  • Proto-Oncogene Proteins c-jun / genetics
  • Proto-Oncogene Proteins p21(ras) / physiology
  • Proto-Oncogene Proteins*
  • Receptors, Interleukin / physiology*
  • Receptors, Interleukin-6
  • Signal Transduction
  • Trans-Activators*
  • Transcription Factors / physiology
  • Tyrosine / analogs & derivatives
  • Tyrosine / metabolism
  • alpha-Macroglobulins / genetics

Substances

  • Antigens, CD
  • DNA-Binding Proteins
  • IL6ST protein, human
  • Il6st protein, mouse
  • Isoquinolines
  • Membrane Glycoproteins
  • Piperazines
  • Protein Kinase Inhibitors
  • Proto-Oncogene Proteins
  • Proto-Oncogene Proteins c-jun
  • Receptors, Interleukin
  • Receptors, Interleukin-6
  • Trans-Activators
  • Transcription Factors
  • alpha-Macroglobulins
  • Cytokine Receptor gp130
  • Phosphotyrosine
  • Tyrosine
  • 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine
  • Protein Kinases
  • Protein-Tyrosine Kinases
  • JAK1 protein, human
  • JAK2 protein, human
  • Jak1 protein, mouse
  • Jak2 protein, mouse
  • Janus Kinase 1
  • Janus Kinase 2
  • HRAS protein, human
  • Proto-Oncogene Proteins p21(ras)