Plasmid-based transgenic mouse model for studying in vivo mutations

Nature. 1995 Oct 19;377(6550):657-9. doi: 10.1038/377657a0.

Abstract

A new transgenic mouse model for studying in vivo somatic mutations is based on the efficient recovery of chromosomally integrated lacZ-containing plasmids, using magnetic beads.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Bacteriophage lambda / genetics
  • Lac Operon
  • Mice
  • Mice, Inbred C57BL
  • Mice, Transgenic*
  • Models, Genetic*
  • Mutation*
  • Plasmids*