Interferon or hepatitis C virus induced autoimmune aplastic anemia and severe thrombocytopenia? A case report

R Siciliano; B A Trovato; G Seminara; V Giustolisi; M Malaguarnera

Interferon or hepatitis C virus induced autoimmune aplastic anemia and severe thrombocytopenia? A case report

Ann Ital Med Int. 1995 Jul-Sep;10(3):193-4.

Authors

R Siciliano¹, B A Trovato, G Seminara, V Giustolisi, M Malaguarnera

Affiliation

¹ Istituto di Medicina Interna e Geriatria, Università degli Studi di Catania.

PMID: 7577317

Abstract

We describe a case of aplastic anemia with severe thrombocytopenia in a patient affected by chronic active hepatitis C treated with interferon. The hematologic alterations did not disappear after suspension of interferon or after the ensuing steroid treatment. Administration of cyclosporin markedly improved the hematologic parameters and serum transaminase levels.

Publication types

Case Reports
Review

MeSH terms

Anemia, Aplastic / diagnosis
Anemia, Aplastic / etiology*
Autoimmune Diseases / diagnosis
Autoimmune Diseases / etiology*
Biopsy, Needle
Bone Marrow / pathology
Bone and Bones / pathology
Chronic Disease
Female
Hepatitis C / complications*
Humans
Interferon Type I / adverse effects*
Middle Aged
Recombinant Proteins
Thrombocytopenia / diagnosis
Thrombocytopenia / etiology*
Time Factors

Substances

Interferon Type I
Recombinant Proteins