Evaluation of repeat administration of a replication deficient, recombinant adenovirus containing the normal cystic fibrosis transmembrane conductance regulator cDNA to the airways of individuals with cystic fibrosis

Hum Gene Ther. 1995 May;6(5):667-703. doi: 10.1089/hum.1995.6.5-667.
No abstract available

MeSH terms

  • Adenoviridae / genetics*
  • Adenoviridae / physiology
  • Adolescent
  • Adult
  • Clinical Protocols
  • Clinical Trials as Topic*
  • Cystic Fibrosis / genetics
  • Cystic Fibrosis / physiopathology
  • Cystic Fibrosis / therapy*
  • Cystic Fibrosis Transmembrane Conductance Regulator / genetics*
  • DNA, Complementary / administration & dosage
  • DNA, Complementary / genetics
  • Female
  • Gene Transfer Techniques
  • Genetic Therapy* / adverse effects
  • Humans
  • Male
  • Recombinant Proteins / genetics
  • Virus Replication

Substances

  • CFTR protein, human
  • DNA, Complementary
  • Recombinant Proteins
  • Cystic Fibrosis Transmembrane Conductance Regulator