A case of a 45 year old male with COPD is presented. In the past the patient required twice mechanical ventilation. During a current hospitalization Nasal Intermittent Positive Pressure Ventilation (NIPPV) was successfully applied. The treatment was carried out continuously for 8 days, during the next 7 days for 15 hours per day, during the next 8 days only at night time. A clinical improvement was seen. NIPPV was used for a shorter period of time than the classical mechanical ventilation. It was also less expensive.