Severe hepatotoxicity from granulocyte-macrophage colony-stimulating factor administered after autologous bone marrow transplantation

H M Prince; M Cheng; R G Cameron; A Keating

Severe hepatotoxicity from granulocyte-macrophage colony-stimulating factor administered after autologous bone marrow transplantation

Bone Marrow Transplant. 1995 Jul;16(1):195-7.

Authors

H M Prince¹, M Cheng, R G Cameron, A Keating

Affiliation

¹ University of Toronto Autologous Blood and Marrow Transplant Program, Toronto Hospital, Ontario, Canada.

PMID: 7581124

Abstract

We report a case of life-threatening hepatotoxicity following GM-CSF therapy after autologous bone marrow transplantation. GM-CSF hepatotoxicity should now be considered in the differential diagnosis of post-transplant liver disease.

Publication types

Case Reports

MeSH terms

Adult
Bone Marrow Transplantation*
Diagnosis, Differential
Graft Rejection / prevention & control
Granulocyte-Macrophage Colony-Stimulating Factor / adverse effects*
Humans
Liver Diseases / diagnosis
Liver Diseases / etiology*
Male
Transplantation, Autologous

Substances

Granulocyte-Macrophage Colony-Stimulating Factor