Unique and common tumor-specific transplantation antigens of chemically induced mouse sarcomas

Int J Cancer. 1978 Mar 15;21(3):317-22. doi: 10.1002/ijc.2910210311.

Abstract

Methylcholanthrene-induced sarcomas of BALB/c mice express unique tumor specific transplantation antigens (TSTA), and weaker, common TSTA. Antigens of endogenous murine leukemia virus (MuLV) expressed by some of these tumors cannot completely account for these common TSTA. However, MuLV antigens on the immunizing tumor appear to increase the immunogenicity of the common TSTA.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Antigens, Neoplasm
  • Cell Line
  • Epitopes
  • Female
  • Histocompatibility Antigens*
  • Leukemia Virus, Murine
  • Methylcholanthrene
  • Mice
  • Mice, Inbred BALB C
  • Neoplasm Transplantation
  • Sarcoma, Experimental / chemically induced
  • Sarcoma, Experimental / immunology*
  • Transplantation, Homologous

Substances

  • Antigens, Neoplasm
  • Epitopes
  • Histocompatibility Antigens
  • Methylcholanthrene