Transverse myelopathy complicating mixed connective tissue disease

Clin Neurol Neurosurg. 1995 Aug;97(3):259-60. doi: 10.1016/0303-8467(95)00045-l.

Abstract

We report the case of a 46-year-old female patient with transverse myelitis complicating mixed connective tissue disease (MCTD). She responded well to steroid and immunosuppressive therapy. Unlike in systemic lupus erythematosus (SLE), transverse myelopathy in association with MCTD is very rarely described. The mechanisms, diagnosis and treatment of transverse myelitis in MCTD are briefly discussed.

Publication types

  • Case Reports

MeSH terms

  • Azathioprine / administration & dosage
  • Dose-Response Relationship, Drug
  • Drug Therapy, Combination
  • Female
  • Glucocorticoids / administration & dosage
  • Humans
  • Immunosuppressive Agents / administration & dosage
  • Middle Aged
  • Mixed Connective Tissue Disease / diagnosis*
  • Mixed Connective Tissue Disease / drug therapy
  • Mixed Connective Tissue Disease / physiopathology
  • Myelitis, Transverse / diagnosis*
  • Myelitis, Transverse / drug therapy
  • Myelitis, Transverse / physiopathology
  • Neurologic Examination / drug effects
  • Prednisone / administration & dosage
  • Spinal Cord / drug effects
  • Spinal Cord / physiopathology

Substances

  • Glucocorticoids
  • Immunosuppressive Agents
  • Azathioprine
  • Prednisone