Non-small-cell lung cancer with multiple paraneoplastic syndromes

Eur Respir J. 1995 Jul;8(7):1231-4. doi: 10.1183/09031936.95.08071231.

Abstract

We describe the case of a patient with multiple paraneoplastic syndromes, six in total, associated with a non-small-cell cancer of the lung. In this single patient we found hypertrophic pulmonary osteoarthropathy, hyperkeratosis of palms and soles, erythema annulare centrifugum, syndrome of inappropriate secretion of antidiuretic hormone (SIADH), and ectopic andrenocorticotrophic hormone (ACTH) and calcitonin production.

Publication types

  • Case Reports

MeSH terms

  • ACTH Syndrome, Ectopic / etiology
  • Adenocarcinoma / complications*
  • Adenocarcinoma / metabolism
  • Adenocarcinoma / pathology
  • Calcitonin / metabolism
  • Carcinoma, Non-Small-Cell Lung / complications*
  • Carcinoma, Non-Small-Cell Lung / metabolism
  • Carcinoma, Non-Small-Cell Lung / pathology
  • Erythema / etiology
  • Humans
  • Inappropriate ADH Syndrome / etiology
  • Keratoderma, Palmoplantar / etiology
  • Lung / pathology
  • Lung Neoplasms / complications*
  • Lung Neoplasms / metabolism
  • Lung Neoplasms / pathology
  • Male
  • Middle Aged
  • Osteoarthropathy, Secondary Hypertrophic / etiology
  • Paraneoplastic Endocrine Syndromes / etiology
  • Paraneoplastic Syndromes / etiology*

Substances

  • Calcitonin