Abstract
A lipid-binding protein identical to the rat intestinal bile acid-binding protein, termed I-15P, was expressed in steroid hormone-producing tissues such as ovary and adrenal gland, but not testis. In immature rats, I-15P was expressed in intestine but not in ovaries. The expression of I-15P in the ovaries of immature rats was induced to the level in immature rats by gonadotropin treatment. This suggests that the expression of I-15P in the ovaries is controlled by the ovarian cycle. The present results indicate that the expression of I-15P is developmentally and hormonally controlled in a tissue-specific manner.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adrenal Glands / metabolism
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Animals
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Carrier Proteins / biosynthesis*
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Carrier Proteins / genetics
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Fatty Acid-Binding Proteins
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Female
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Gastrointestinal Hormones
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Gene Expression Regulation
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Gonadotropins / pharmacology
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Hydroxysteroid Dehydrogenases*
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Intestinal Mucosa / metabolism
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Male
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Membrane Glycoproteins*
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Ovary / metabolism
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Rats
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Rats, Sprague-Dawley
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Testis / metabolism
Substances
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Carrier Proteins
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Fatty Acid-Binding Proteins
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Gastrointestinal Hormones
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Gonadotropins
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Membrane Glycoproteins
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bile acid binding proteins
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fatty acid-binding protein 6
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Hydroxysteroid Dehydrogenases
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AKR1C2 protein, human