Treatment of experimental rabbit infective endocarditis due to a multidrug-resistant Pseudomonas aeruginosa with high-dose ceftazidime alone and combined with amikacin or sulbactam or both

J Antimicrob Chemother. 1995 May;35(5):697-706. doi: 10.1093/jac/35.5.697.
No abstract available

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amikacin / administration & dosage
  • Amikacin / blood
  • Amikacin / pharmacology*
  • Animals
  • Aortic Valve*
  • Ceftazidime / administration & dosage
  • Ceftazidime / blood
  • Ceftazidime / pharmacology
  • Drug Administration Schedule
  • Drug Resistance, Microbial
  • Drug Resistance, Multiple
  • Drug Therapy, Combination
  • Endocarditis / drug therapy*
  • Endocarditis / microbiology
  • Female
  • Heart Valve Diseases / drug therapy
  • Microbial Sensitivity Tests
  • Pseudomonas Infections / drug therapy*
  • Pseudomonas aeruginosa* / drug effects
  • Rabbits
  • Sulbactam / administration & dosage
  • Sulbactam / blood
  • Sulbactam / pharmacology*
  • beta-Lactamases / biosynthesis

Substances

  • Amikacin
  • Ceftazidime
  • beta-Lactamases
  • Sulbactam