Isolation, purification and characterization of porcine serum transferrin and hemopexin

Comp Biochem Physiol B Biochem Mol Biol. 1995 Jun;111(2):171-9. doi: 10.1016/0305-0491(94)00255-s.

Abstract

Two techniques are described for the isolation of porcine serum transferrin and hemopexin, respectively, yielding nearly pure proteins (> 99%) as tested with crossed immunoelectrophoresis. Porcine transferrin has an estimated molecular weight of 79 kDa and porcine hemopexin a molecular weight of 62 kDa. Both purified proteins were subjected to amino acid and carbohydrate analyses. Based on carbohydrate and sialic acid analyses, it is proposed that transferrin contains one bi-antennary glycan chain, whereas hemopexin contains two bi-antennary and one tri-antennary glycan chains.

MeSH terms

  • Amino Acids / analysis
  • Animals
  • Carbohydrate Sequence
  • Hemopexin / chemistry
  • Hemopexin / isolation & purification*
  • Molecular Sequence Data
  • Molecular Weight
  • Swine
  • Transferrin / chemistry
  • Transferrin / isolation & purification*

Substances

  • Amino Acids
  • Transferrin
  • Hemopexin