Intra-arterial infusion chemotherapy in combination with a biscoclaurine alkaloid, Cepharanthin, to treat bone metastasis arising from renal cell carcinoma

Y Shichiri; T Kanba; S Yoshida; Y Arai; Y Kakehi; O Yoshida

doi:10.1111/j.1442-2042.1994.tb00063.x

Intra-arterial infusion chemotherapy in combination with a biscoclaurine alkaloid, Cepharanthin, to treat bone metastasis arising from renal cell carcinoma

Int J Urol. 1994 Dec;1(4):349-51. doi: 10.1111/j.1442-2042.1994.tb00063.x.

Authors

Y Shichiri¹, T Kanba, S Yoshida, Y Arai, Y Kakehi, O Yoshida

Affiliation

¹ Department of Urology, Faculty of Medicine, Kyoto University, Japan.

PMID: 7614400
DOI: 10.1111/j.1442-2042.1994.tb00063.x

Abstract

A 64-year-old man with iliac bone metastasis from left renal cell carcinoma was treated by intra-arterial infusion chemotherapy using vinblastine and epirubicine in combination with a biscoclaurine alkaloid, Cepharanthin. A good response was confirmed by computed tomography scan and the symptoms related to the metastatic lesion were much improved. Partial resection of the left iliac bone was performed when no viable cancer cells were found in the metastatic lesion.

Publication types

Case Reports

MeSH terms

Alkaloids / therapeutic use*
Angiography
Antineoplastic Agents, Phytogenic / therapeutic use*
Antineoplastic Combined Chemotherapy Protocols / administration & dosage*
Benzylisoquinolines
Biopsy
Bone Neoplasms / blood supply
Bone Neoplasms / drug therapy*
Bone Neoplasms / secondary*
Carcinoma, Renal Cell / pathology*
Epirubicin / therapeutic use
Humans
Ilium / diagnostic imaging
Injections, Intra-Arterial
Kidney Neoplasms / pathology*
Male
Middle Aged
Recurrence
Tomography, X-Ray Computed
Vinblastine / therapeutic use

Substances

Alkaloids
Antineoplastic Agents, Phytogenic
Benzylisoquinolines
Epirubicin
Vinblastine
cepharanthine