Abstract
Metastatic disease tends to recur after remission of Ewing's sarcoma. The effectiveness of ifosfamide in patients with recurrent Ewing's sarcoma was reported in recent years. We administered IFOS combined with etoposide, pirarubicin, and cyclophosphamide to 4 Ewing's sarcoma patients with metastatic disease, and succeeded in inducing second remissions in all cases.
MeSH terms
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Adolescent
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Adult
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Antineoplastic Combined Chemotherapy Protocols / adverse effects
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
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Bone Neoplasms / drug therapy*
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Bone Neoplasms / pathology
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Cyclophosphamide / administration & dosage
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Doxorubicin / administration & dosage
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Doxorubicin / analogs & derivatives
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Drug Administration Schedule
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Etoposide / administration & dosage
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Humans
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Ifosfamide / administration & dosage
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Male
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Salvage Therapy*
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Sarcoma, Ewing / drug therapy*
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Sarcoma, Ewing / secondary
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Treatment Outcome
Substances
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Etoposide
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Doxorubicin
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Cyclophosphamide
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pirarubicin
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Ifosfamide