Changes in the activity of metabolic and non-metabolic liver enzymes in rats following co-administration of gossypol with phenobarbital

Pharmacol Toxicol. 1995 Apr;76(4):289-91. doi: 10.1111/j.1600-0773.1995.tb00145.x.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Biotransformation
  • Cytosol / drug effects
  • Cytosol / enzymology
  • Drug Interactions
  • Enzymes / metabolism*
  • Gossypol / administration & dosage
  • Gossypol / pharmacology*
  • Injections, Intraperitoneal
  • Male
  • Microsomes, Liver / drug effects
  • Microsomes, Liver / enzymology*
  • Phenobarbital / administration & dosage
  • Phenobarbital / pharmacology*
  • Rats
  • Rats, Sprague-Dawley

Substances

  • Enzymes
  • Gossypol
  • Phenobarbital