Early experience with stretch polytetrafluoroethylene grafts for haemodialysis access surgery: results of a prospective randomised study

Eur J Vasc Endovasc Surg. 1995 Apr;9(3):305-9. doi: 10.1016/s1078-5884(05)80135-2.

Abstract

Objective: The purpose of this study was to evaluate the results and complications of standard ePTFE versus stretch ePTFE AV fistulas.

Design: Prospective randomised trial.

Setting: University Hospital.

Materials: During a 2-year period 37 patients received 17 stretch and 20 standard ePTFE graft AV fistulas.

Chief outcome measures: Patients were evaluated for the occurrence of complications and graft patency. Regular Duplex scans were performed to detect stenoses in the fistula circuit.

Main results: Thrombotic events occurred in 40% of the standard ePTFE grafts, compared to 12% of the stretch ePTFE prostheses (p < 0.001). The incidence of puncture complications was similar in both groups. The cumulative primary patency rate in the stretch ePTFE group was significantly higher compared to the standard ePTFE group (1-year patency rates of 59% and 29%, respectively; p < 0.01). No differences in the duration of puncture site bleeding were observed. Duplex scanning showed a significantly greater number of stenoses in the standard ePTFE grafts.

Conclusions: The new stretch ePTFE prosthesis has better primary patency rates and less stenoses due to intimal hyperplasia as compared to standard ePTFE grafts.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Arm / blood supply
  • Arteriovenous Shunt, Surgical / adverse effects
  • Arteriovenous Shunt, Surgical / instrumentation*
  • Blood Vessel Prosthesis*
  • Female
  • Graft Occlusion, Vascular / diagnostic imaging
  • Graft Occlusion, Vascular / epidemiology*
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • Polytetrafluoroethylene*
  • Prospective Studies
  • Punctures / adverse effects
  • Renal Dialysis*
  • Thrombosis / diagnostic imaging
  • Thrombosis / epidemiology*
  • Time Factors
  • Ultrasonography
  • Vascular Patency

Substances

  • Polytetrafluoroethylene