Abstract
The structures and properties of the Rad51 and Rad52 proteins in eukaryotes are described. Both proteins form a complex and are responsible for recombination and repair reactions. The N-terminal region of the Rad51 protein interacts with the C-terminal region of the Rad52 protein. Species-specific interaction is probably essential for the functioning of these genes.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Animals
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Biophysical Phenomena
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Biophysics
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Cloning, Molecular
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DNA Repair / genetics
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DNA-Binding Proteins / genetics*
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Eukaryotic Cells
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Fungal Proteins / genetics*
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Humans
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Rad51 Recombinase
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Saccharomyces cerevisiae / genetics
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Saccharomyces cerevisiae Proteins
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Schizosaccharomyces / genetics
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Schizosaccharomyces pombe Proteins*
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Species Specificity
Substances
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DNA-Binding Proteins
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Fungal Proteins
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RHP51 protein, S pombe
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Saccharomyces cerevisiae Proteins
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Schizosaccharomyces pombe Proteins
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RAD51 protein, S cerevisiae
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RAD51 protein, human
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Rad51 Recombinase