Antidiabetic agents: a new class of reversible carnitine palmitoyltransferase I inhibitors

J Med Chem. 1995 Sep 1;38(18):3448-50. doi: 10.1021/jm00018a003.
No abstract available

MeSH terms

  • 3-Hydroxybutyric Acid
  • Administration, Oral
  • Animals
  • Blood Glucose / metabolism
  • Carnitine O-Palmitoyltransferase / antagonists & inhibitors*
  • Cells, Cultured
  • Drug Design
  • Fatty Acids / metabolism
  • Hydroxybutyrates / metabolism
  • Hypoglycemic Agents / chemistry
  • Hypoglycemic Agents / classification
  • Hypoglycemic Agents / pharmacology*
  • Liver / enzymology
  • Organophosphonates / chemistry
  • Organophosphonates / pharmacology*
  • Oxidation-Reduction
  • Rats
  • Structure-Activity Relationship

Substances

  • Blood Glucose
  • Fatty Acids
  • Hydroxybutyrates
  • Hypoglycemic Agents
  • Organophosphonates
  • Carnitine O-Palmitoyltransferase
  • 3-Hydroxybutyric Acid