Abstract
Twenty patients with hepatocellular carcinoma were studied by dynamic sequential inversion recovery snap shot fast low angle shot (FLASH) imaging after the bolus injection of various amounts of Gd-DTPA. We determined the optimal dose of Gd-DTPA for depicting tumors as early marked enhancement and compared the method with dynamic CT by matching data acquisition time. The optimal dose was estimated to be 0.1 mmol/kg. Compared with dynamic CT, dynamic MRI showed rapid short-term enhancement in the early phase, while the contrast enhancement in the late phase lasted longer and was stronger than that of CT.
Publication types
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Clinical Trial
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Comparative Study
MeSH terms
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Aged
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Carcinoma, Hepatocellular / diagnosis*
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Carcinoma, Hepatocellular / diagnostic imaging
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Contrast Media
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Female
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Gadolinium DTPA
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Gadolinium* / administration & dosage
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Humans
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Liver Neoplasms / diagnosis*
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Liver Neoplasms / diagnostic imaging
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Magnetic Resonance Imaging / methods*
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Male
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Middle Aged
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Organometallic Compounds* / administration & dosage
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Pentetic Acid / administration & dosage
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Pentetic Acid / analogs & derivatives*
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Predictive Value of Tests
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Tomography, X-Ray Computed
Substances
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Contrast Media
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Organometallic Compounds
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Pentetic Acid
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Gadolinium
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Gadolinium DTPA