The molecular design of human IL-6 receptor antagonists

Ann N Y Acad Sci. 1995 Jul 21:762:136-50; discussion 150-1. doi: 10.1111/j.1749-6632.1995.tb32322.x.
No abstract available

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Antigens, CD*
  • Cytokine Receptor gp130
  • Humans
  • Interleukin-6 / chemistry*
  • Interleukin-6 / metabolism
  • Membrane Glycoproteins / chemistry*
  • Membrane Glycoproteins / metabolism
  • Models, Molecular
  • Molecular Sequence Data
  • Mutagenesis, Site-Directed
  • Protein Structure, Tertiary
  • Receptors, Interleukin / antagonists & inhibitors*
  • Receptors, Interleukin / chemistry
  • Receptors, Interleukin / metabolism
  • Receptors, Interleukin-6
  • Sequence Alignment
  • Sequence Homology, Amino Acid
  • Structure-Activity Relationship

Substances

  • Antigens, CD
  • IL6ST protein, human
  • Interleukin-6
  • Membrane Glycoproteins
  • Receptors, Interleukin
  • Receptors, Interleukin-6
  • Cytokine Receptor gp130