Residues 77-95 of the human interleuken-6 protein are responsible for receptor binding and residues 41-56 for signal transduction

Ann N Y Acad Sci. 1995 Jul 21:762:400-2. doi: 10.1111/j.1749-6632.1995.tb32347.x.
No abstract available

MeSH terms

  • Animals
  • Antigens, CD*
  • Binding Sites
  • Cytokine Receptor gp130
  • Humans
  • Interleukin-6 / chemistry*
  • Interleukin-6 / metabolism
  • Lymphocyte Activation
  • Membrane Glycoproteins / chemistry
  • Membrane Glycoproteins / metabolism
  • Mice
  • Receptors, Interleukin / metabolism*
  • Receptors, Interleukin-6
  • Signal Transduction
  • Structure-Activity Relationship

Substances

  • Antigens, CD
  • IL6ST protein, human
  • Il6st protein, mouse
  • Interleukin-6
  • Membrane Glycoproteins
  • Receptors, Interleukin
  • Receptors, Interleukin-6
  • Cytokine Receptor gp130