Premature labor and intra-amniotic infection. Clinical aspects and role of the cytokines in diagnosis and pathophysiology

R Gomez; F Ghezzi; R Romero; H Muñoz; J E Tolosa; I Rojas

Premature labor and intra-amniotic infection. Clinical aspects and role of the cytokines in diagnosis and pathophysiology

Clin Perinatol. 1995 Jun;22(2):281-342.

Authors

R Gomez¹, F Ghezzi, R Romero, H Muñoz, J E Tolosa, I Rojas

Affiliation

¹ Perinatology Research Branch, National Institute of Child Health and Human Development, Bethesda, Maryland, USA.

PMID: 7671540

Abstract

The role of infection in the pathogenesis of preterm labor and delivery, and the specific mechanisms through which this association is demonstrated are presented. Cellular and biochemical changes that initiate parturition in the setting of infection are discussed, particularly prostaglandins and cytokines.

Publication types

Review

MeSH terms

Animals
Bacterial Infections / diagnosis
Bacterial Infections / physiopathology*
Chorioamnionitis / diagnosis
Chorioamnionitis / microbiology*
Chorioamnionitis / physiopathology
Cytokines / physiology*
Female
Humans
Infant, Newborn
Labor, Obstetric / physiology
Obstetric Labor, Premature / diagnosis
Obstetric Labor, Premature / microbiology*
Obstetric Labor, Premature / physiopathology
Pregnancy
Pregnancy Complications, Infectious / physiopathology
Prostaglandins / physiology
Uterine Diseases / microbiology
Uterine Diseases / physiopathology

Substances

Cytokines
Prostaglandins