One-hundred and five patients with ASA I-II were scheduled for general surgery. Atracurium was the muscle-relaxant of choice. A bolus dose of atracurium (0.5 mg/kg-1) was administered immediately before thiopentone. After 15 minutes began the infusion of atracurium diluited in saline solution and administered through a simple infusion set. The neuromuscolar function was investigated evaluating the amplitude of response to TOF and DBS. This procedure proved to be safe, reliable and easily performed in every operating room.