Raynaud phenomenon in three patients with acquired immune deficiency syndrome-related Kaposi sarcoma treated with bleomycin

Cancer. 1993 Sep 15;72(6):2004-6. doi: 10.1002/1097-0142(19930915)72:6<2004::aid-cncr2820720635>3.0.co;2-5.

Abstract

The authors report three cases of Raynaud phenomenon that developed during doxorubicin, bleomycin, and vincristine (ABV) therapy for acquired immune deficiency syndrome (AIDS)-related Kaposi sarcoma. Although Raynaud phenomenon is well documented as a side effect of bleomycin, vinblastine, and cisplatin chemotherapy for germ cell neoplasms, it has not been widely documented in patients with AIDS.

Publication types

  • Case Reports

MeSH terms

  • Acquired Immunodeficiency Syndrome / complications*
  • Adult
  • Antineoplastic Combined Chemotherapy Protocols / adverse effects
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Bleomycin / administration & dosage
  • Bleomycin / adverse effects*
  • Doxorubicin / administration & dosage
  • Doxorubicin / adverse effects
  • HIV Seropositivity / complications
  • Humans
  • Male
  • Raynaud Disease / chemically induced*
  • Sarcoma, Kaposi / complications*
  • Sarcoma, Kaposi / drug therapy
  • Vinblastine / administration & dosage
  • Vinblastine / adverse effects

Substances

  • Bleomycin
  • Vinblastine
  • Doxorubicin

Supplementary concepts

  • VBA protocol