Salivary up-regulation of human polymorphonuclear leucocyte chemotaxis and adhesion-molecule expression

F Pettini; P Pettini; A Laforgia; M Coluccia; P De Rinaldis; R Fumarulo

doi:10.1016/0003-9969(94)90088-4

Salivary up-regulation of human polymorphonuclear leucocyte chemotaxis and adhesion-molecule expression

Arch Oral Biol. 1994 Nov;39(11):1007-9. doi: 10.1016/0003-9969(94)90088-4.

Authors

F Pettini¹, P Pettini, A Laforgia, M Coluccia, P De Rinaldis, R Fumarulo

Affiliation

¹ Odontostomatologic Clinic, University of Bari, Italy.

PMID: 7695504
DOI: 10.1016/0003-9969(94)90088-4

Abstract

Chemotaxis and adhesion molecules were investigated in peripheral blood neutrophils incubated with saliva collected from healthy donors. A salivary concentration of 20% increased chemotactic responses and CD11a/CD18 and CD11b/CD18 expression, but had no effect on formyl-methionyl-leucyl-phenylalanine receptors.

MeSH terms

Adult
CD11 Antigens / biosynthesis
CD11 Antigens / immunology
CD18 Antigens / biosynthesis
CD18 Antigens / immunology
Chemotaxis, Leukocyte / immunology*
Dental Plaque / immunology
Humans
N-Formylmethionine Leucyl-Phenylalanine / immunology
N-Formylmethionine Leucyl-Phenylalanine / metabolism
Neutrophil Activation
Neutrophils / immunology*
Receptors, Formyl Peptide
Receptors, Immunologic / biosynthesis
Receptors, Immunologic / immunology
Receptors, Leukocyte-Adhesion / biosynthesis*
Receptors, Leukocyte-Adhesion / immunology
Receptors, Peptide / biosynthesis
Receptors, Peptide / immunology
Saliva / immunology*
Up-Regulation

Substances

CD11 Antigens
CD18 Antigens
Receptors, Formyl Peptide
Receptors, Immunologic
Receptors, Leukocyte-Adhesion
Receptors, Peptide
N-Formylmethionine Leucyl-Phenylalanine