N-(1-methyl-5-indolyl)-N'-(3-methyl-5-isothiazolyl)urea: a novel, high-affinity 5-HT2B receptor antagonist

J Med Chem. 1995 Mar 17;38(6):855-7. doi: 10.1021/jm00006a001.

Authors

I T Forbes¹, G E Jones, O E Murphy, V Holland, G S Baxter

Affiliation

¹ SmithKline Beecham Pharmaceuticals, Discovery Research, Harlow, Essex, England.

PMID: 7699699
DOI: 10.1021/jm00006a001

No abstract available

MeSH terms

Animals
Humans
Indoles / chemical synthesis*
Indoles / pharmacology*
Rats
Receptors, Serotonin / metabolism*
Serotonin Antagonists / chemical synthesis*
Serotonin Antagonists / pharmacology*
Urea / analogs & derivatives*
Urea / chemical synthesis
Urea / metabolism
Urea / pharmacology

Substances

Indoles
N-(1-methyl-5-indolyl)-N'-(3-methyl-5-isothiazolyl)urea
Receptors, Serotonin
Serotonin Antagonists
Urea