Intrathecal gene therapy for the treatment of leptomeningeal carcinomatosis. GTI 0108. A phase I/II study

Hum Gene Ther. 1995 Jan;6(1):55-85. doi: 10.1089/hum.1995.6.1-55.
No abstract available

Publication types

  • Clinical Trial
  • Clinical Trial, Phase I
  • Clinical Trial, Phase II

MeSH terms

  • Adult
  • Aged
  • Carcinoma / drug therapy
  • Carcinoma / therapy*
  • Clinical Protocols
  • Ganciclovir / therapeutic use*
  • Genetic Therapy*
  • Humans
  • Injections, Intraventricular
  • Injections, Spinal
  • Meningeal Neoplasms / drug therapy
  • Meningeal Neoplasms / therapy*
  • Middle Aged
  • Simplexvirus / enzymology
  • Simplexvirus / genetics
  • Thymidine Kinase / genetics*
  • Thymidine Kinase / therapeutic use

Substances

  • Thymidine Kinase
  • Ganciclovir