MRI of intracranial germ cell tumours

Neuroradiology. 1995 Jan;37(1):32-7. doi: 10.1007/BF00588516.

Abstract

We reviewed MRI findings in proven intracranial germ cell tumours in 22 cases, 12 of whom received Gd-DTPA. On T1-weighted images, the signal intensity of the tumour parenchyma was moderately low in 19 cases and isointense in 3; on T2-weighted images, it was high in all cases. Regions of different intensity thought to be cysts were found in 17 (77%): 7 of 12 patients with germinoma (58%) and in all other cases. Of the 13 patients with pineal lesions T1-weighted sagittal images showed the aqueduct to be obstructed in 5, stenotic in 7 and normal in 1. Strong contrast enhancement was observed in all 12 cases. Of the 14 patients with suprasellar lesions, 5 were found to have an intrasellar extension, and in 3 of these, the normal pituitary gland, which could be distinguished from the tumour, was displaced anteriorly. Ten patients (45%) had multiple lesions.

MeSH terms

  • Adolescent
  • Adult
  • Brain / pathology
  • Brain Neoplasms / diagnosis*
  • Brain Neoplasms / pathology
  • Child
  • Child, Preschool
  • Contrast Media
  • Diagnosis, Differential
  • Female
  • Gadolinium DTPA
  • Germinoma / diagnosis*
  • Germinoma / pathology
  • Humans
  • Infant
  • Magnetic Resonance Imaging*
  • Male
  • Organometallic Compounds
  • Pentetic Acid / analogs & derivatives
  • Pineal Gland / pathology
  • Pinealoma / diagnosis
  • Pinealoma / pathology

Substances

  • Contrast Media
  • Organometallic Compounds
  • Pentetic Acid
  • Gadolinium DTPA