Use of safety-modified retroviruses to introduce chemotherapy resistance sequences into normal hematopoietic cells for chemoprotection during the therapy of ovarian cancer: a pilot trial

Hum Gene Ther. 1994 Dec;5(12):1507-22. doi: 10.1089/hum.1994.5.12-1507.
No abstract available

Publication types

  • Clinical Trial

MeSH terms

  • Adolescent
  • Adult
  • Clinical Protocols
  • Combined Modality Therapy
  • DNA, Complementary / administration & dosage
  • Drug Resistance, Multiple / genetics*
  • Feasibility Studies
  • Female
  • Genetic Therapy* / adverse effects
  • Hematopoietic Stem Cells / physiology*
  • Humans
  • Middle Aged
  • Ovarian Neoplasms / therapy*
  • Paclitaxel / therapeutic use
  • Pilot Projects
  • Reference Values
  • Retroviridae / genetics*
  • Transduction, Genetic

Substances

  • DNA, Complementary
  • Paclitaxel