Determination of normal human fetal immunoglobulin M levels

Clin Diagn Lab Immunol. 1995 Jan;2(1):115-7. doi: 10.1128/cdli.2.1.115-117.1995.

Abstract

Immunoglobulin M (IgM) levels were measured in 198 cord blood samples from 192 apparently normal pregnancies from 24 weeks of gestation to term. Simple linear regression analysis yielded a standard curve for IgM development during pregnancy showing a 0.5 mg/dl increase in IgM per week of gestation. This curve allows the comparison of fetal IgM levels from pregnancies considered to be at risk for intrauterine infection.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cordocentesis
  • Female
  • Fetal Blood / immunology*
  • Fetal Diseases / blood
  • Fetal Diseases / diagnosis
  • Fetal Diseases / immunology
  • Gestational Age
  • Humans
  • Immunoglobulin M / blood*
  • Infant, Newborn
  • Infant, Premature
  • Infections / blood
  • Infections / diagnosis
  • Infections / embryology
  • Infections / immunology
  • Obstetric Labor, Premature
  • Pregnancy
  • Prenatal Diagnosis
  • Regression Analysis

Substances

  • Immunoglobulin M