AIDS-related Kaposi sarcoma of the lung: radiographic findings and staging system with bronchoscopic correlation

Radiology. 1995 May;195(2):545-52. doi: 10.1148/radiology.195.2.7724781.

Abstract

Purpose: To determine the chest radiographic findings in patients with tracheobronchial Kaposi sarcoma (KS) and to develop a radiographic staging system that allows comparison of radiographic to bronchoscopic findings and allows assessment of the typical temporal progression of pulmonary KS.

Materials and methods: The chest radiographs and medical records of 76 male patients, aged 23-60 years (mean, 36 years 4 months) with bronchoscopically proved KS were retrospectively reviewed. Tumor extent at bronchoscopy (grade 1-3) was compared with severity of parenchymal disease (radiographic stage 0-3).

Results: There was a statistically significant relationship between extent of tracheobronchial disease and radiographic stage (P = .01). However, in some patients, parenchymal KS of advanced stage was present with no visible endobronchial disease.

Conclusion: The proposed staging system describes features of early, moderate, and advanced KS. Although there is a correlation between tracheobronchial and parenchymal disease, the latter can occur in the absence of endobronchial lesions.

MeSH terms

  • Acquired Immunodeficiency Syndrome / complications*
  • Adult
  • Bronchoscopy
  • Humans
  • Lung / diagnostic imaging
  • Lung Neoplasms / diagnostic imaging*
  • Lung Neoplasms / etiology
  • Lung Neoplasms / pathology
  • Male
  • Neoplasm Staging
  • Pleural Effusion, Malignant / diagnostic imaging
  • Radiography
  • Retrospective Studies
  • Sarcoma, Kaposi / diagnostic imaging*
  • Sarcoma, Kaposi / etiology
  • Sarcoma, Kaposi / pathology
  • Tracheal Neoplasms / diagnostic imaging*
  • Tracheal Neoplasms / etiology
  • Tracheal Neoplasms / pathology