Indications for coronary angiography depend on the patient's clinical presentation. In many situations, coronary angiography may be reserved for patients who have severe symptoms, despite optimal medical therapy, and for patients defined to be at high risk, based on noninvasive stress testing. These patient groups include those with chest pain syndromes, postmyocardial infarction, unstable angina, postcoronary revascularization, severe left ventricular dysfunction, survivors of sudden cardiac death, and those about to undergo major vascular noncardiac surgery.