Short- and long-term prognostic implications of in-hospital postinfarction arrhythmias. DAVIT II Study Group

Cardiology. 1995;86(1):49-55. doi: 10.1159/000176830.

Abstract

The purpose of the present study was to evaluate, in patients surviving the first postinfarction week, the short- and long-term prognostic implications of arrhythmias, and their relation to easily obtained anamnestic and clinical parameters presented during hospitalisation. The study consisted of 897 placebo-treated patients of the Danish Verapamil Infarction Trial II (DAVIT II). In patients with and without supraventricular tachycardia mortality within 2 months was 9.2 and 3.7% (p = 0.004), respectively. By multivariate analysis supraventricular tachycardia independently predicted mortality within 2 months. Mortality within 5 years was predicted by the presence of supraventricular tachycardia, atrial fibrillation, advanced atrioventricular block, sinoatrial block, and of the combined arrhythmic parameter, i.e. ventricular and/or atrial fibrillation and/or advanced atrioventricular block. When easily obtained and assessed anamnestic and clinical parameters were included in a multivariate analysis, the presence of supraventricular tachycardia alone gave independent prognostic information on long-term mortality.

Publication types

  • Clinical Trial
  • Clinical Trial, Phase II
  • Randomized Controlled Trial

MeSH terms

  • Aged
  • Arrhythmias, Cardiac / complications*
  • Arrhythmias, Cardiac / drug therapy
  • Arrhythmias, Cardiac / mortality
  • Humans
  • Multivariate Analysis
  • Myocardial Infarction / complications*
  • Myocardial Infarction / drug therapy
  • Prognosis
  • Verapamil / therapeutic use

Substances

  • Verapamil