The authors analyse their experience of 20 hepatic resections of metastatic malignant lesion to the liver from non-colorectal primary neoplasms: tubal or ovarian adenocarcinoma (3 cases), digestive adenocarcinoma (6 cases), sarcoma (3 cases) and endocrine malignancies (8 cases). Then, they discuss the justification of such aggressive approach, the type of hepatic resection that has to be done and the date of the procedure according to the characteristics of the secondary neoplasm (synchronous or metachronous). The histological type of the primary malignancy is an important factor in this debate.